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Best setup for Barrows - Guthan the Infested in OSRS

The best setup for Barrows - Guthan the Infested in OSRS is magic with a Tumeken's shadow, which does 11.64 DPS with a max hit of 70 and 99.7% accuracy at level-99 stats. The full best-in-slot gear, prayer and potion for every combat style are listed below.

The highest-DPS melee, ranged and magic loadouts against Barrows - Guthan the Infested, computed with wiki-accurate combat math at maxed (99) stats. Open any setup in the calculator to swap in the gear you own.

🔮 Magic Best DPS
Tumeken's shadow Tumeken's shadow
11.64DPS
70Max hit
99.7%Accuracy
10.5sAvg TTK
  • Ancestral hatAncestral hat
  • Imbued guthix capeImbued guthix cape
  • Occult necklaceOccult necklace
  • Rada's blessing 4Rada's blessing 4
  • Tumeken's shadowTumeken's shadow
  • Ancestral robe topAncestral robe top
  • Ancestral robe bottomAncestral robe bottom
  • Confliction gauntletsConfliction gauntlets
  • Avernic treads (et)Avernic treads (et)
  • Magus ringMagus ring
Prayer: Augury Potion: Saturated heart
Open in DPS calculator →
⚔️ Melee
Soulreaper axe Soulreaper axe
7.60DPS
74Max hit
61.6%Accuracy
16.3sAvg TTK
  • Oathplate helmOathplate helm
  • Infernal capeInfernal cape
  • Amulet of rancourAmulet of rancour
  • Rada's blessing 4Rada's blessing 4
  • Soulreaper axeSoulreaper axe
  • Oathplate chestOathplate chest
  • Oathplate legsOathplate legs
  • Ferocious glovesFerocious gloves
  • Avernic treads (max)Avernic treads (max)
  • Bellator ringBellator ring
Prayer: Piety Potion: Super combat
Open in DPS calculator →
🏹 Ranged
Bow of faerdhinen Bow of faerdhinen
7.36DPS
49Max hit
72.0%Accuracy
15.8sAvg TTK
  • Crystal helmCrystal helm
  • Dizana's quiverDizana's quiver
  • Necklace of ruptureNecklace of rupture
  • Bow of faerdhinenBow of faerdhinen
  • Crystal bodyCrystal body
  • Crystal legsCrystal legs
  • Zaryte vambracesZaryte vambraces
  • Avernic treads (max)Avernic treads (max)
  • Venator ringVenator ring
Prayer: Rigour Potion: Ranging potion
Open in DPS calculator →

Barrows - Guthan the Infested has a scripted fight — see Barrows - Guthan the Infested kill times in the fight simulator to run these builds through the real phased kill tick by tick.

Assumes level-99 combat stats and the best relevant prayer and potion, off Slayer task (no Slayer-helmet bonus). DPS is single-target on the boss's base stats; magic setups consider powered staves. Numbers come from RuneBuddy's WASM combat engine, the same one behind the DPS calculator.

Barrows - Guthan the Infested setup FAQ

What is the best setup for Barrows - Guthan the Infested in OSRS?
The best setup for Barrows - Guthan the Infested in OSRS is magic with a Tumeken's shadow, which does 11.64 DPS with a max hit of 70 and 99.7% accuracy at level-99 stats. The full best-in-slot gear, prayer and potion for every combat style are listed below.
What is the best melee setup for Barrows - Guthan the Infested?
The best melee setup for Barrows - Guthan the Infested uses a Soulreaper axe for 7.60 DPS, with Piety and a super combat.
What is the best ranged setup for Barrows - Guthan the Infested?
The best ranged setup for Barrows - Guthan the Infested uses a Bow of faerdhinen for 7.36 DPS, with Rigour and a ranging potion.
What is the best magic setup for Barrows - Guthan the Infested?
The best magic setup for Barrows - Guthan the Infested uses a Tumeken's shadow for 11.64 DPS, with Augury and a saturated heart.
How long does it take to kill Barrows - Guthan the Infested?
With the best setup (Tumeken's shadow), Barrows - Guthan the Infested takes about 10.5 seconds per kill against its base stats. RuneBuddy's Boss Fight Simulator runs the real phased fight tick by tick for a true kill-time spread.

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